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DENTAL MATERIALS SELF ASSESSMENT PROGRAMME

Question 12: Endodontics

Biocompatibility of sealer cements. It is generally recommended that the results of a range of tests (cytotoxicity, mutagenicity, histocompatibility, clinical usage) be taken into account in determining the biocompatibility of a sealer cement, rather than relying on a single test such as cytotoxicity.

Why is cytotoxicity testing insufficient for predicting clinical suitability of a sealer cement?


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